Category
Mannitol Pellets
SNC00686
Mannitol, a sugar alcohol, is widely used in pharmaceutical formulations and food products due to its unique physical and chemical properties. It is a stable crystalline non-hygroscopic solid, freely soluble in water (18.6% w/w at 20°C), and chemically inert. Being a non-reducing sugar alcohol, mannitol does not undergo Maillard reactions with amines, making it highly compatible with most drugs.
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Product Details
Functions of Mannitol Pellets
- Bulking Agent:
- Freeze-Dried Injectable Products: Mannitol Pellets is commonly used as a bulking agent in freeze-dried injectable products. Mannitol Pellets increases the cake mass and prevents blowout during the freeze-drying process, resulting in a mechanically robust and pharmaceutically elegant lyophile.
- Oral Dispersible and Chewable Tablets: Mannitol Pellets is the filler of choice for orally dispersible and chewable tablets due to its high solubility, pleasant taste, and mouthfeel. Mannitol Pellets provides a cool sensation when dissolved in the mouth and does not raise blood glucose levels or have a laxative effect.
- Cryoprotector:
- Freeze-Drying: Mannitol Pellets can be used as a cryoprotector in freeze-drying processes, helping to maintain the stability and integrity of biological molecules during the freezing and drying steps.
- Drug Carrier:
- Nasal and Pulmonary Delivery Systems: Mannitol Pellets is used as a drug carrier in nasal and pulmonary delivery systems, facilitating the penetration of drugs through biological barriers.
Applications of Mannitol Pellets
- Pharmaceutical Formulations:
- Tablets: Mannitol Pellets is used as a diluent in tablet formulations, particularly in orally disintegrating tablets (ODTs) and chewable tablets. Its non-hygroscopic nature and brittle fracture during compression make it ideal for these applications.
- Injectables: Mannitol Pellets is added to many liquid injectable formulations to modify osmolarity and is used therapeutically as a diuretic and to reduce intracranial pressure.
- Food Products:
- Confectionery: Mannitol Pellets is used in confectionery products due to its sweet taste and low hygroscopicity, providing a pleasant mouthfeel and extended shelf life.
- Medical Devices:
- Dry Powder Inhalers: Mannitol Pellets is approved in the EU as a dry powder formulation for the add-on therapy in adult cystic fibrosis patients (Bronchitol®). Its osmotic effect changes the viscoelastic properties of mucus, increasing liquid content and thus improving mucociliary clearance.
FAQ
1.DO YOU ACCEPT SAMPLE ORDER?
Yes. We support sample orders for your trial production. And after the sample approved, we can negotiate for commercial order.
2.HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
We support free sample, you only need to pay the shipping cost or arrange a courier to us and take the samples. We can also provide customized materials according to your specification demands.
3.WHAT'S YOUR MOQ?
Our don’t have MOQ restriction, even 1kg is available from us.
4. IS THERE A DISCOUNT?
Depends on the quantity you take. Different quantity has different discount.
Our Advantage
Almost 20 Years Experience
Our products are sold worldwide, like Europe, North&South America, Asia and pacific area as well as Africa, we are aiming to establish long term cooperation with our clients.
One-Stop Service
Committed to supplying healthy raw materials to the world, providing the highest quality raw materials for the world's health products, sports supplements, cosmetics, pharmaceuticals and other fields. Customized product is also available from us.
Our products are sold worldwide, like Europe, North&South America, Asia and pacific area as well as Africa, we are aiming to establish long term cooperation with our clients.
One-Stop Service
Committed to supplying healthy raw materials to the world, providing the highest quality raw materials for the world's health products, sports supplements, cosmetics, pharmaceuticals and other fields. Customized product is also available from us.
7 DAYS 24 HOURS service
In time and clear response to customers questions. 100% guaranteed aftersales service, we are happy to provide guidance or solutions during your consumption.
Quality Assurance
Dedicated to provide high-quality materials for customers with reasonable price.
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