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anti-inflammatory

Mangostin

SNC00711
Mangostin, a bioactive compound found in the pericarp of Garcinia mangostana, has recently gained attention for its potential health benefits. Mangostin is classified as a xanthone, characterized by a xanthoney ring structure. Its molecular formula is C28H26O10, with a molecular weight of 542.48 g/mol. The compound features a planar structure with multiple substituents, including hydroxyl groups, methoxyl groups, and isomethoxyl groups, which contribute to its distinctive biological activities.
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Research has demonstrated that mangostin possesses a variety of biological activities, primarily centered around antioxidant, anti-inflammatory, and anticancer effects.

1.Antioxidant Activity: Mangostin exhibits strong antioxidant properties, capable of scavenging free radicals such as superoxide anions (O2-) and hydroxyl radicals (OH-). This activity prevents lipid peroxidation and safeguards cellular membranes from oxidative damage.

2.Anti-inflammatory Activity: Mangostin inhibits the production of inflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6). Additionally, mangostin suppresses the activity of cyclooxygenase (COX) and lipoxygenase (LOX), thereby reducing prostaglandin and le prostaglandin synthesis and alleviating inflammatory responses.

3.Anticancer Activity: Mangostin has been shown to inhibit the proliferation of various cancer cells, such as breast cancer, lung cancer, and colon cancer cells. Mangostin induces apoptosis in cancer cells by activating caspase-3 and caspase-9 while inhibiting the expression of anti-apoptotic proteins like Bcl-2 and Bcl-xl. Furthermore, mangostin interferes with the formation of cancer cell colonies and diminishes their invasive and metastatic capacities by inhibiting matrix metalloproteinase (MMP) activity.

4.Antibacterial Activity: Mangostin can restrain the growth of multiple pathogenic bacteria, exerting effective antibacterial effects.

  FAQ  

1.DO YOU ACCEPT SAMPLE ORDER?
Yes. We support sample orders for your trial production. And after the sample approved, we can negotiate for commercial order.


2.HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
We support free sample, you only need to pay the shipping cost or arrange a courier to us and take the samples. We can also provide customized materials according to your specification demands.


3.WHAT'S YOUR MOQ?
Our don’t have MOQ restriction, even 1kg is available from us.

4. IS THERE A DISCOUNT?
Depends on the quantity you take. Different quantity has different discount.

 

  Our Advantage  

Almost 20 Years Experience
Our products are sold worldwide, like Europe, North&South America, Asia and pacific area as well as Africa, we are aiming to establish long term cooperation with our clients.

One-Stop Service
Committed to supplying healthy raw materials to the world, providing the highest quality raw materials for the world's health products, sports supplements, cosmetics, pharmaceuticals and other fields. Customized product is also available from us.
 

7 DAYS 24 HOURS service

In time and clear response to customers questions. 100% guaranteed aftersales service, we are happy to provide guidance or solutions during your consumption.

Quality Assurance
Dedicated to provide high-quality materials for customers  with reasonable price.

 
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