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Trimethoprim

Trimethoprim

SNC00811
Trimethoprim (TMP) is an oral synthetic antibacterial agent belonging to the diaminopyrimidine class. It exerts its antimicrobial effect by selectively inhibiting bacterial dihydrofolate reductase, an enzyme critical for synthesizing tetrahydrofolic acid—an essential nutrient for bacterial DNA, RNA, and protein production. This inhibition disrupts bacterial growth, though it rarely works alone due to potential resistance. Clinically, TMP is most commonly combined with sulfamethoxazole (forming co-trimoxazole) to treat infections like urinary tract infections (UTIs), respiratory tract infections, and certain opportunistic infections in immunocompromised patients. It is also used solo for uncomplicated UTIs in some cases. Common side effects include nausea, rash, and mild gastrointestinal upset, while rare but serious reactions may involve blood disorders or liver toxicity. Dosage adjusts based on patient age, renal function, and infection type, and it should be used cautiously in pregnant women or those with kidney impairments.
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 Trimethoprim 
 

Trimethoprim, commonly abbreviated as TMP, is a synthetic antibiotic widely used to treat infections caused by bacteria. Trimethoprim functions by inhibiting the enzyme dihydrofolate reductase, which is crucial for the synthesis of folic acid—an essential nutrient required by bacteria for growth and replication. By blocking this enzyme, Trimethoprim effectively disrupts the bacterial metabolic pathway, leading to their death.

This antibiotic, Trimethoprim, is frequently prescribed for urinary tract infections, respiratory infections, and certain skin conditions. Trimethoprim's effectiveness and relatively low incidence of side effects make it a popular choice among healthcare providers. Trimethoprim is often combined with sulfamethoxazole (SMX) to form the well-known antibiotic Bactrim, which broadens its spectrum of activity against a wider range of bacterial pathogens.

Selective Antibacterial Feature: It barely interferes with human dihydrofolate reductase at therapeutic doses, so it exerts targeted bactericidal effects with little disruption to human normal folate metabolism.

Despite its widespread use, Trimethoprim is important to note that Trimethoprim should be used judiciously to prevent the development of antibiotic resistance. Trimethoprim's targeted action on bacterial enzymes underscores its importance in modern medicine, providing a valuable tool in the fight against bacterial infections while emphasizing the need for responsible antibiotic use.

  FAQ  

1.DO YOU ACCEPT SAMPLE ORDER?
Yes. We support sample orders for your trial production. And after the sample approved, we can negotiate for commercial order.


2.HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
We support free sample, you only need to pay the shipping cost or arrange a courier to us and take the samples. We can also provide customized materials according to your specification demands.


3.WHAT'S YOUR MOQ?
Our don’t have MOQ restriction, even 1kg is available from us.

4. IS THERE A DISCOUNT?
Depends on the quantity you take. Different quantity has different discount.

 

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In time and clear response to customers questions. 100% guaranteed aftersales service, we are happy to provide guidance or solutions during your consumption.

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