Category
β-Nicotinamide adenine dinucleotide - Nad+
Product Details
Product Name: | β-Nicotinamide adenine dinucleotide（Nad+) |
β-Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme found in all living cells, playing a crucial role in numerous cellular processes. Here are some of its primary uses and functions:
1. Redox Reactions: β-Nicotinamide adenine dinucleotide (NAD+) acts as an electron carrier in redox reactions, transferring electrons from one reaction to another. This is essential for cellular respiration and energy production.
2. Energy Metabolism: β-Nicotinamide adenine dinucleotide (NAD+) plays a key role in glycolysis, the citric acid cycle (also known as the Krebs cycle or TCA cycle), and oxidative phosphorylation, which are processes that generate ATP, the cell's energy currency.
3. Sirtuins Activation: β-Nicotinamide adenine dinucleotide (NAD+) is a substrate for sirtuins, a family of proteins that regulate deacetylation reactions involved in processes like DNA repair, metabolic regulation, and cell survival.
4. Epigenetic Regulation: β-Nicotinamide adenine dinucleotide (NAD+) is involved in the ADP-ribosylation process, which modifies proteins and DNA, affecting gene expression and playing a role in immune responses and cellular stress responses.
5. Neurotransmitter and Neuromodulator: Recent research suggests that NAD+ may function as a neurotransmitter and neuromodulator in the peripheral nervous system, affecting neuronal signaling.
6. Natural Product Biosynthesis: β-Nicotinamide adenine dinucleotide (NAD+) serves as a building block in the assembly of certain natural products, indicating its role in secondary metabolite biosynthetic pathways.
7. DNA Repair: β-Nicotinamide adenine dinucleotide (NAD+) is a cofactor for poly(ADP-ribose) polymerase (PARP) enzymes, which are involved in the repair of DNA damage.
8. Aging and Health: β-Nicotinamide adenine dinucleotide (NAD+) levels decline with age, and its replenishment has been linked to improved cellular health and potentially extended lifespan.
9. Alcohol Metabolism: β-Nicotinamide adenine dinucleotide (NAD+) is used by alcohol dehydrogenase (ADH) to oxidize ethanol in the liver.
10. Commercial Applications: In molecular biology and biotechnology, NAD+ is supplied in solutions for use in biochemical assays and enzymatic reactions, such as in PCR repair mixes.
11. Mitochondrial quality control: NAD⁺ participates in modulating mitochondrial biogenesis and mitophagy, supporting the clearance of damaged mitochondria and maintaining intracellular mitochondrial homeostasis.
β-Nicotinamide adenine dinucleotide (NAD+) is an essential molecule for life, and its decline with age or deficiency can lead to various health issues.
FAQ
1.DO YOU ACCEPT SAMPLE ORDER?
Yes. We support sample orders for your trial production. And after the sample approved, we can negotiate for commercial order.
2.HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
We support free sample, you only need to pay the shipping cost or arrange a courier to us and take the samples. We can also provide customized materials according to your specification demands.
3.WHAT'S YOUR MOQ?
Our don’t have MOQ restriction, even 1kg is available from us.
4. IS THERE A DISCOUNT?
Depends on the quantity you take. Different quantity has different discount.
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